Junior chairs in the field of research on mitochondria The Laboratory of Excellence (LabEx) MitoCross announces the call for applications for two junior chairs in the field of research on mitochondria.
We welcome XuChu Duan, a visiting researcher from the Nantong University! XuChu, who is a specialist in zebrafish and developmental biology, is doing his sabbatical in our team. He will work on the mechanistic roles of YBEY in coordination of the human…
New publication of the MITO team in Nucleic Acids Research Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24. pii: gkab1227. doi: 10.1093/nar/gkab1227. Online ahead of…
USIAS 2020 award for Alexandre Smirnov The Institute for Advanced Studies at the University of Strasbourg (USIAS) is committed to supporting an original type of research and potentially pioneering research, so as to…
Junior chairs in the field of research on mitochondria The Laboratory of Excellence (LabEx) MitoCross announces the call for applications for two junior chairs in the field of…
We welcome XuChu Duan, a visiting researcher from the Nantong University! XuChu, who is a specialist in zebrafish and developmental biology, is doing his sabbatical in our team. He will work on…
New publication of the MITO team in Nucleic Acids Research Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24.…
New publication of the MITO team in Nucleic Acids Research YBEY is an essential biogenesis factor for mitochondrial ribosomes Nucleic Acids Res. 2020 Mar 17. pii: gkaa148. doi:…
USIAS 2020 award for Alexandre Smirnov The Institute for Advanced Studies at the University of Strasbourg (USIAS) is committed to supporting an original type…
Anne-Marie Heckel à la rencontre des Lycéens Anne-Marie Heckel, ingénieure de l'équipe MITO, avait présenté nos thématiques de recherche aux lycéens. La rencontre a…
Le projet d’École Universitaire de recherche en biologie moléculaire et cellulaire intégrative incluant le LabEx MitoCross - lauréat du Programme d’investissements d’avenir. Basé sur un regroupement stratégique des forces strasbourgeoises en biologie moléculaire et cellulaire des trois…
Le consortium MitoCross se dote d'un site web ! L'objectif global du consortium MitoCross est d'approfondir les connaissances et mécanismes moléculaires fins gouvernant…
LabEx : La Mitochondrie Strasbourgeoise à l'Honneur 2 équipes de l'unité ont été labélisées MitoCross Le projet Laboratoires d’Excellence (LabEx) Investissement d’Avenir…
New publication of the MITO team in Nucleic Acids Research Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24. pii: gkab1227. doi: 10.1093/nar/gkab1227. Online ahead of print. Regina Shebanova 1, Natalia Nikitchina 1 2, Nikita Shebanov 1, Vladimir Mekler 3, Konstantin Kuznedelov 3, Egor…
Our paper in collaboration with the Alya Venyaminova's team has been published in Molecules Meschaninova MI, Entelis NS, Chernolovskaya EL, Venyaminova AG (2021) A versatile solid-phase approach to the synthesis of oligonucleotide conjugates with biodegradable hydrazone linker. Molecules 26:2119 One of the ways to efficiently deliver various drugs, including therapeutic nucleic acids,…
Congratulations on a fantastic 2021 series of review & protocol papers from the MITO team! Our big review on stable RNPs and the complexomic approaches to profile them , including Grad-seq, co-authored with the Jörg Vogel's lab, is availbale in Frontiers in Molecular Biosciences: Gerovac M, Vogel J, Smirnov A (2021) The world of stable ribonucleoproteins and its mapping with Grad-seq…
A FASEB J. paper by the MITO team The FASEB Journal Early View RESEARCH ARTICLE Open Access Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria Viola Mazzoleni Gaëlle Zimmermann-Meisse Anna Smirnova Ivan Tarassov Gilles Prévost First…
New publication by MITO team in Neurology: Genetics Karine Auré, Guillemette Fayet, Ivan Chicherin, Benoit Rucheton, Sandrine Filaut, Anne-Marie Heckel, Julie Eichler, Florence Caillon, Yann Péréon, Nina Entelis, Ivan Tarassov, Anne Lombès (2020) A homoplasmic mitochondrial tRNAPro mutation causing exercise-induced muscle swelling and fatigue.…
New publication of the MITO team in Nucleic Acids Research YBEY is an essential biogenesis factor for mitochondrial ribosomes Nucleic Acids Res. 2020 Mar 17. pii: gkaa148. doi: 10.1093/nar/gkaa148. [Epub ahead of print] Summer S1, Smirnova A2, Gabriele A2, Toth U1, Fasemore AM3, Förstner KU3,4,5, Kuhn L6, Chicher J6, Hammann P6, Mitulovi? G7, Entelis N2, …
New paper in IUBMB life by MITO-team. IUBMB Life. 2018 Sep 5. doi: 10.1002/iub.1919. [Epub ahead of print] Can Mitochondrial DNA be CRISPRized: Pro and Contra. Loutre R1, Heckel AM1, Smirnova A1, Entelis N1, Tarassov I1. Author information Abstract Mitochondria represent a chimera of macromolecules encoded either in the…
New paper in PLoS ONE for the MITO-team R. Loutre, AM Heckel, D Jeandard, I Tarassov, N Entelis (2018) "Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner" PLOS ONE https://doi.org/10.1371/journal.pone.0199258 Abstract Mutations in mitochondrial DNA are an important source of…
MITO-Team : paper accepted in BIOMATERIALS I. Dovydenko, I. Tarassov, A. Venyaminova, N. Entelis (2015) Method of carrier-free delivery of therapeutic RNA importable into human mitochondria: lipophilic conjugates with cleavable bonds. Biomaterials (in press) BIOMATERIALS is one of the leading journals in the field of molecular therapy and…