All publications

Douglas J, Cui H, Perona JJ, Vargas-Rodriguez O, Tyynismaa H, Carreño CA, Ling J, Ribas de Pouplana L, Yang XL, Ibba M, Becker H, Fischer F, Sissler M, Carter Jr CW, Wills PR (2024) AARS Online: A collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases. IUBMB Life, https://doi.org/10.1002/iub.2911

El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, Körner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P (2024) Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nat Cell Biol 26:1154–64

Nikitchina N, Ulashchik E, Shmanai V, Heckel AM, Tarassov I, Mazunin I, Entelis N (2024) Targeting of CRISPR-Cas12a crRNAs into human mitochondria. Biochimie,  10.1016/j.biochi.2023.09.006

Gruffaz C, Smirnov A (2023) GTPase Era at the heart of ribosome assembly. Front Mol Biosci 10:1263433

Jeandard D, Smirnova A, Fasemore AM, Coudray L, Entelis N, Förstner KU, Tarassov I, Smirnov A (2023) CoLoC-seq probes the global topology of organelle transcriptomes. Nucleic Acids Res 51:e16

Liao Z & Smirnov A (2023) FinO/ProQ-family proteins: an evolutionary perspective. Biosci Rep 43:BSR20220313

Smirnov A (2023) Research progress in RNA-binding proteins. Int J Mol Sci 24:58

Smirnova A, Jeandard D, Smirnov A (2023) Controlled Level of Contamination Coupled to Deep Sequencing (CoLoC-seq) probes the global localisation topology of organelle transcriptomes. Bio-protocol 13: e4820

Burzio VA, Barrey E, Leucci E, Entelis N, Hollander JM and Das S (2022) Editorial: Role of mitochondria-associated noncoding RNAs in intracellular communication. Front Physiol 13:980674

Smirnov A (2022) How global RNA-binding proteins coordinate the behaviour of RNA regulons: an information approach. Comput Struct Biotechnol J 20:6317-38

Vasilev R, Gunitseva N, Shebanova R, Korzhenkov A, Vlaskina A, Evteeva M, Polushkina I, Nikitchina N, Toshchakov S, Kamenski P, Patrushev M, Mazunin I (2022) Targeted modification of mammalian DNA by a novel type V Cas12a endonuclease from Ruminococcus bromii. Int J Mol Sci 23:9289

Shebanova R, Nikitchina N, Shebanov N, Mekler V, Kuznedelov K, Ulashchik E, Vasilev R, Sharko O, Shmanai V, Tarassov I, Severinov K, Entelis N, Mazunin I (2021) Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA. Nucleic Acids Res 50:1162-73

Meschaninova MI, Entelis NS, Chernolovskaya EL, Venyaminova AG (2021) A versatile solid-phase approach to the synthesis of oligonucleotide conjugates with biodegradable hydrazone linker. Molecules 26:2119

Gerovac M, Vogel J, Smirnov A (2021) The world of stable ribonucleoproteins and its mapping with Grad-seq and related approaches. Front Mol Biosci 8:661448

Liao Z, Schelcher C, Smirnov A (2021) YbeY, éminence grise of ribosome biogenesis. Biochem Soc Trans 49:727-45

Smirnova A, Richert L, Smirnov A, Mély Y, Tarassov I (2021) Suborganellar localisation of mitochondrial proteins and transcripts in human cells. Methods Mol Biol 2277:157-73

Dovydenko I, Meschaninova M, Heckel AM, Tarassov I, Venyaminova A, Entelis N (2021) Lipophilic conjugates for carrier-free delivery of RNA importable into human mitochondria. Methods Mol Biol 2277:49-67

Mazzoleni V, Zimmermann-Meisse G, Smirnova A, Tarassov I, Prévost G (2020) Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria. FASEB J 35:e21167

Auré K, Fayet G, Chicherin I, Rucheton B, Filaut S, Heckel AM, Eichler J, Caillon F, Péréon Y, Entelis N, Tarassov I, Lombès A (2020) A homoplasmic mitochondrial tRNAPro mutation causing exercise-induced muscle swelling and fatigue. Neurol Genet 6:e480

Summer S, Smirnova A, Gabriele A, Toth U, Fasemore AM, Forstner KU, Kuhn L, Chicher J, Hammann P, Mitulovic G, Entelis N, Tarassov I, Rossmanith W, Smirnov A (2020) YBEY is an essential biogenesis factor for mitochondrial ribosomes. Nucleic Acids Res 48:9762–86

Jeandard D, Smirnova A, Tarassov I, Barrey E, Smirnov A, Entelis N (2019) Import of non-coding RNAs into human mitochondria: a critical review and emerging approaches. Cells 8, 286

Meyer M, Walbott H, Olieric V, Kondo J, Costa M, Masquida B (2019) Conformational adaptation of UNCG loops upon crowding. RNA 25:1522-31

Kamenski PA, Krasheninnikov IA, Tarassov I (2019) 40 years of studying RNA import into mitochondria: from basic mechanisms to gene therapy strategies. Mol Biol (Mosk) 53:924-32

Loutre R, Heckel AM, Smirnova A, Entelis N, Tarassov I (2018) Can mitochondrial DNA be CRISPRized: pro and contra. IUBMB Life 70:1233-9

Loutre R, Heckel AM, Jeandard D, Tarassov I, Entelis N (2018) Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner. PLoS ONE 13:e0199258

Smirnov A, Schneider C, Hör J, Vogel J (2017) Discovery of new classes and global RNA-binding proteins. Curr Opin Microbiol 39:152-60

Namer LS, Osman F, Banai Y, Masquida B, Jung R, Kaempfer R (2017) An ancient pseudoknot in TNF-alpha pre-mRNA activates PKR, inducing eIF2alpha phosphorylation that potently enhances splicing. Cell Rep 20:188-200

Chicherin IV, Levitsky SA, Krasheninnikov IA, Tarassov I, Kamenski P (2017) The prospects of gene therapy of for mitochondrial diseases: can’t we do without CRISPR/Cas9? Bulletin of RSMU 3:43-7

Baleva MV, Meyer M, Entelis N, Tarassov I, Kamenski P, Masquida B (2017) Factors beyond Enolase 2 and mitochondrial lysyl-tRNA synthetase precursor are required for tRNA import into yeast mitochondria. Biochemistry (Mosc) 82:1324-35

Angulo J, Ulryck N, Deforges J, Chamond N, Lopez-Lastra M, Masquida B, Sargueil B. (2016) LOOP IIId of the HCV IRES is essential for the structural rearrangement of the 40S-HCV IRES complex. Nucleic Acids Res 44:1309-25

Dovydenko I, Veniaminova A, Pyshnyi D, Tarassov I, Entelis N (2016) Modifications in therapeutic oligonucleotides improving the delivery. In: Nucleic Acids Modifications, Springer series (J. Barciszewski, Ed.), pp. 319-337

Smirnova EV, Chicherin IV, Baleva MV, Entelis N, Tarassov I, Kamenski PA (2016) PreMsk1p purification and tRNA import. Biochemistry (Mosc) 81:1081-8

Meyer M, Masquida B (2016) Polyacrylamide gel electrophoresis for purification of large amounts of RNA. Methods Mol Biol 1320:59-65

Andersen KL, Beckert B, Masquida B, Johansen SD, Nielsen H (2016) Accumulation of stable full-length circular group I intron RNAs during heat-shock. Molecules 21:1541-1558

Fernandez-Millan P, Schelcher C, Chihade J, Masquida B, Giege P, Sauter C (2016) Transfer RNA: From pioneering crystallographic studies to contemporary tRNA biology. Arch Biochem Biophys 602:95-105

Dovydenko I, Tarassov I,  Venyaminova A, Entelis N (2015) Method of carrier-free delivery of therapeutic RNA importable into human mitochondria: lipophilic conjugates with cleavable bonds.Biomaterials 76:408-17

Dovydenko I, Heckel AM, Tonin Y, Gowher A, Venyaminova A, Tarassov I, Entelis N (2015) Mitochondrial targeting of recombinant RNA. Methods Mol Biol 1265:209-25

Baleva M, Gowher A, Kamenski P, Tarassov I, Entelis N, Masquida B (2015) A moonlighting human protein is involved in mitochondrial import of tRNA. Int J Mol Sci 16:9354-67

Tarassov I, Entelis N (2014) New Vector for Therapy of Mitochondrial Disease.Patent US 62/011,755

Tonin Y, Entelis N (2014) Mitochondrial DNA diseases and therapeutic strategies. Med Sci (Paris) 30:1101-9

Kondo J, Sauter C, Masquida B (2014) RNA Crystallization. In: Handbook of RNA biochemistry: Second, Completely Revised and Enlarged Edition (Hartmann, R.K., Bindereif, A., Schön, A., Westhof, E., eds.) pp. 481-498. Wiley-VCH

Meyer M, Nielsen H, Oliéric V, Roblin P, Johansen SD, Westhof E, Masquida B (2014) Speciation of a group I intron into a lariat capping ribozyme. Proc Natl Acad Sci USA 111:7659-64

Tonin Y, Heckel AM, Vysokikh M, Dovydenko I, Meschaninova M,  Rötig A, Munnich A, Venyaminova A, Tarassov I, Entelis N (2014)Modelling of antigenomic therapy of mitochondrial diseases by mitochondrially addressed RNA targeting a pathogenic point mutation in mtDNA.J Biol Chem 289:13323-34

Maréchal-Drouard L, Sissler M, Tarassov I (2014) Mitochondria: An organelle for life. Biochimie 100:1-2

Tonin Y, Heckel AM, Dovydenko I, Meschaninova M, Comte C, Venyaminova A, Pyshnyi D, Tarassov I, Entelis N (2014) Characterization of chemically modified oligonucleotides targeting a pathogenic mutation in human mitochondrial DNA. Biochimie 100:192-9

Meyer M, Masquida B (2014) Cis-acting 5' Hammerhead ribozyme optimization for in vitro transcription of highly structured RNAs. Methods Mol Biol 1086:21-40

Tarassov I, Chicherin I, Tonin Y, Smirnov A, Kamenski P, Entelis N (2013) Mitochondrial targeting of RNA and mitochondrial translation. In: A.-M. Duchene (ed.), Translation in mitochondria and other organelles, Springer-Verlag Berlin Heidelberg, pp.85-107

Gowher A, Smirnov A, Tarassov I, Entelis N (2013) Induced tRNA import into human mitochondria: implication of a host aminoacyl-tRNA-synthetase. PLoS ONE 8:e66228

Comte C, Tonin Y, Heckel-Mager AM, Boucheham A, Smirnov A, Auré K, Lombès A, Martin RP, Entelis N, Tarassov I (2013) Mitochondrial targeting of recombinant RNAs modulates the level of a heteroplasmic mutation in human mitochondrial DNA associated with Kearns Sayre Syndrome. Nucleic Acids Res 41:418-33

Vedrenne V, Gowher A, De Lonlay P, Nitschke P, Serre V, Boddaert N, Aaltuzarra C, Mager-Heckel AM, Chretien F, Entelis N, Munnich A, Tarassov I, Rötig A (2012)Mutation in PNPT1, which encodes a polyribonucleotide nucleotidyltransferase, impairs RNA import into mitochondria and causes respiratory chain deficiency.Am J Hum Genet 91:912-8

Kanga S, Bernard D, Mager-Heckel AM, Erpapazoglou Z, Mattiroli F, Sixma TK, Léon S, Urban-Grimal D, Tarassov I, Haguenauer-Tsapis R (2012) A deubiquitylating complex required for neosynthesis of a yeast mitochondrial ATP synthase subunit. PLoS ONE 7:e38071

Smirnova EV, Lakunina VA, Tarassov I, Krasheninnikov IA, Kamenski PA (2012) Noncanonical functions of aminoacyl-tRNA synthetases. Biochemistry (Mosc) 77:21-33

Atkinson GC, Kuzmenko A, Kamenski P, Vysokikh MY, Lakunina V, Tankov S, Smirnova E, Soosaar A, Tenson T, Hauryliuk V (2012) Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae. Nucleic Acids Res 40:6122-6134

Belostotsky R, Frishberg Y, Entelis N (2012) Human mitochondrial tRNA quality control in health and disease: a channeling mechanism?RNA Biol 9:33-9

Kuzmenko A, Tankov S, English BP, Tarassov I, Tenson T, Kamenski P, Elf J, Hauryliuk V (2011) Single molecule tracking fluorescence microscopy reveals highly dynamic but confined nature of Tom40 movement. Sci Rep 1:195

Karicheva O, Kolesnikova O, Schirtz T, Vysokikh M, Mager-Heckel AM, Lombès A, Boucheham A, Krasheninnikov I, Martin RP, Entelis N, Tarassov I (2011) Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria. Nucleic Acids Res 39:8173-86

Smirnov A, Entelis N, Martin R, Tarassov I (2011)Mitochondrial import of 5S rRNA in human cells: role of the MRP-L18 protein and biological significance. Genes Dev 25:1289-305

Smirnov A, Comte C, Addis V, Mager-Heckel AM, Krasheninnikov I, Martin R, Entelis N, Tarassov I (2010) Mitochondrial enzyme rhodanese is essential for 5 S ribosomal RNA import into human mitochondria. J Biol Chem 285:30792-803

Kamenski P, Smirnova E, Kolesnikova O, Krasheninnikov I, Martin RP, Entelis N, Tarassov I (2010) tRNA mitochondrial import in yeast: mapping of the import determinants in the carrier protein, the precursor of mitochondrial lysyl-tRNA synthetase. Mitochondrion 10:284-93

Kolesnikova O, Kazakova H, Comte C, Steinberg S, Kamenski P, Martin R, Tarassov I, Entelis N (2010) Selection of RNA aptamers imported into yeast and human mitochondria. RNA 16:926-41

Frechin M, Senger B, Kern D, Martin RP, Becker HD (2010) Arc1p: anchoring, routing, coordinating. FEBS Lett 584:427-33

Zeharia A, Shaag A, Pappo O, Mager-Heckel AM, Saada A, Beinat M, Karicheva O, Mandel H, Ofek N, Segel R, Marom D, Rötig A, Tarassov I, Elpeleg O(2009) Acute liver failure of infancy is caused by mutations in the TRMU gene. Am J Hum Genet 85:401-7

Frenchin M, Senger B, Brayé M, Kern D, Martin RP, Becker HD (2009) Yeast mitochondrial Gln-tRNAGln is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS. Genes Dev 23:1119-30

Smirnov A, Tarassov I, Mager-Heckel AM, Letzelter M, Martin RP, Krasheninnikov I, Entelis N (2008) Two distinct structural elements of 5S rRNA are needed for its import into human mitochondria. RNA 14:749-59

Smirnov A, Entelis NS, Krasheninnikov IA, Martin RP, Tarassov IA (2008) Specific features of 5S rRNA structure - its interactions with macromolecules and possible functions.Biochemistry (Mosc) 73:1418-37

Mager-Heckel AM, Brandina I, Kamenski P, Entelis N, Martin RP, Tarassov I (2007) Methods of analysis of tRNA import into human mitochondria. Methods Mol Biol 372:235-53

Kamenskii PA, Vinogradova EN, Krasheninnikov IA, Tarassov IA (2007) Directed import of macromolecules into mitochondria. Mol Biol (Mosk) 41:187-202

Rustin P, Jacobs HT, Dietrich A, Lightowlers RN, Tarassov I, Corral-Debrinski M (2007) Adresser du matériel allogène dans le compartiment mitochondrial : Des outils nouveaux pour mieux comprendre la physiologie mitochondriale et une perspective pour la thérapie. Med Sci (Paris) 23:519-25

Kamenski P, Kolesnikova O, Jubenot V, Entelis N, Krasheninnikov I, Martin RP, Tarassov I (2007) Evidence for an adaptation mechanism of mitochondrial translation via tRNA import from the cytosol. Mol Cell 26:625-37

Edvardson S, Shaag A, Kolesnikova O, Gomori JM, Tarassov I, Einbinder T, Saada A, Elpeleg O (2007) Deleterious mutation in the mitochondrial arginyl-tRNA synthetase gene is associated with ponto-cerebellar hypoplasia. Am J Hum Genet 81:857-62

Brandina I, Smirnov A, Kolesnikova O, Entelis N, Krasheninnikov IA, Martin RP, Tarassov I (2007) tRNA import into yeast mitochondria is regulated by the ubiquitine-proteasome system. FEBS Lett 581:4248-54

Tarassov I, Kamenski P,Kolesnikova O, Karicheva O, Martin RP, Krasheninnikov IA, Entelis N (2007)Import of nuclear DNA-encoded RNAs into mitochondria and mitochondrial translation. Cell Cycle 20:2473-7

Entelis NS, Brandina IL, Kamenski PA, Krasheninnikov IA, Martin RP, Tarassov I (2006) A glycolytic enzyme, enolase, is recruited as a co-factor of tRNA targeting towards mitochondria in Saccharomyces cerevisiae. Genes Dev 20:1609-20

Brandina I, Graham J, Lemaitre-Guiller C, Entelis N, Krasheninnikov I, Sweetlove L, Tarassov I, Martin RP (2006) Enolase takes part in a macromolecular complex associated to mitochondria in yeast. Biochim Biophys Acta 1757:1217-28

Kolesnikova OA, Entelis NS, Jacquin-Becker C, Goltzene F, Chrzanowska-Lightowlers Z, Lightowlers RN, Martin RP, Tarassov I (2004) Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells. Hum Mol Genet 13:2519-34

Kolesnikova OA, Entelis NS, Krasheninnikov IA, Martin RP, Tarassov IA (2004) tRNA import into mitochondria (a review). Progress in Biological Chemistry 44:53-78

Brandina I, Tarassov I (2003) Import d'ARN dans les mitochondries. Regard sur la Biochimie 4:19-26

Entelis N, Kolesnikova OA, Kazakova EA, Brandina IL, Kamenski PA, Martin RP, Tarassov IA (2002) Import of nuclear encoded RNAs into yeast and human mitochondria: experimental approaches and possible biomedical applications. Genet Eng (NY) 24:191-213

Kolesnikova O, Entelis N, Kazakova H, Brandina I, Martin RP, Tarassov I (2002) Targeting of tRNA into mitochondria: the role of anticodon nucleotides. Mitochondrion 2:95-107

Entelis NS, Kolesnikova OA, Martin RP, Tarassov IA (2001) Importation d'ARNt et maladies mitochondriales. Med Sci (Paris) 17:91-3

Entelis NS, Kolesnikova OA, Martin RP, Tarassov IA (2001) RNA delivery into mitochondria. Adv Drug Deliv Rev 49:199-215

Entelis NS, Kolesnikova OA, Dogan S, Martin RP, Tarassov IA (2001) 5 S rRNA and tRNA import into human mitochondria: comparison of in vitro requirements. J Biol Chem 276:45642-53

Kolesnikova OA, Entelis NS, Mireau H, Fox TD, Martin RP, Tarassov IA (2000) Suppression of mutations in mitochondrial DNA by tRNAs imported from the cytoplasm. Science 289:1931-3

Grava S, Dumoulin P, Madania A, Tarassov IA, Winsor B (2000) Functional Analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential nuclear gene and YNL059c/ARP5 as a strain-dependent essential nuclear gene. Yeast 16:1025-33

Sidorik LL, Rybinska TA, Bakhiya NG, Rodnin NV, Filonenko VV, Entelis NS, Tarassov IA, Martin RP, Matsuka GK (2000) The immunological cross-reactivity between cytoplasmic and mitochondrial mammalian lysyl-tRNA synthetases.Biopolymers and Cell (Kiev) 16:350-7

Tarassov IA, Entelis NS, Martin R (1999) tRNA import into yeast mitochondria: experimental approaches and possible applications. In: Mitochondrial diseases (Lestienne, ed.) Springer-Verlag Berlin Heidelberg, pp. 303-316

Kazakova HA, Entelis NS, Martin RP, Tarassov IA (1999) The aminoacceptor stem of the yeast tRNA^Lys contains determinants of mitochondrial import selectivity.FEBS Lett 442:193-7

Entelis NS, Kieffer S, Kolesnikova OA, Martin R, Tarassov IA (1998) tRNA^Lys structural requirements for its import into yeast mitochondria. Proc Natl Acad Sci USA 95:2838-43

Bordonné R, Camasses A, Madania A, Poch O, Tarassov IA, Winsor B, Martin R (1997) Analysis of a 35.6 kb region on the right arm of Saccharomyces cerevisiae chromosome XV. Yeast 13:73-83

Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonné R, Boyer J, Camasses A, Casamayor A, Casas C, Chéret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Galisson F, Gamo FJ, Gancedo C, Goffeau A, Goulding SE, Grivell LA, Habbig B, Hand NJ, Hani J, Hattenhorst U, Hebling U, Hernando Y, Herrero E, Heumann K, Hiesel RU, Hilger FN, Hofmann BM, Hollenberg, CPS, Hughes BV, Jauniaux JCK, Kalogeropoulos A, Katsoulou C, Kordes E, Lafuente MJ, Landt O, Louis EJ, Maarse AC, Madania A, Mannhaupt G, Marck C, Martin RP, Mewes HW, Michaux G, Paces V, Parle-McDermott AG, Pearson BMT, Perrin AA, Pettersson BAA, Poch OI, Pohl TMV, Poirey RK, Portetelle D, Pujol A, Purnelle B, Ramezani Rad M, Rechmann S, Schwager C, Schweizer M, Sor F, Sterky F, Tarassov IA, Teodoru C, Tettelin H, Thierry A, Tobiasch E, Tzermia M, Uhlen M, Unseld M, Valens M, Vandenbol M, Vetter I, Vlcek C, Voet M, Volckaert G, Voss H, Wambutt R, Wedler H, Wiemann S, Winsor B, Wolfe KH, Zollner A, Zumstein E, Kleine K (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Nature 387:98-102

Entelis NS, Krasheninnikov IA, Martin RP, Tarassov IA (1996) Mitochondrial import of tRNA^Lys_CUU in yeast: possible roles of modified nucleotides and aminoacylation. FEBS Lett 384:38-42

Bordonné R, Tarassov I (1996) The yeast SME1 gene encodes the functional homologue of the human Sm E core protein. Gene 176:111-7

Madania A, Poch O, Tarassov IA, Winsor B, Martin R (1996) Analysis of a 22956 bp region on the right arm of Saccharomyces cerevisiae chromosome XV. Yeast 12:1563-73

Kazakova EA, Tarassov IA, Entelis NS (1996) RNA import into mitochondria. Mol Biol (Mosk) 30:748-58

Tarassov IA, Martin RP (1996) Mechanisms of tRNA import in yeast: An overview. Biochimie 78:502-10

Tarassov I, Entelis N, Martin RP (1995) An intact protein translocating machinery is required for mitochondrial import of a yeast cytoplasmic tRNA. J Mol Biol 245:315-23

Tarassov I, Entelis N, Martin RP (1995) Mitochondrial import of a cytoplasmic lysine-tRNA in yeast is mediated by cooperation of cytoplasmic and mitochondrial lysyl-tRNA synthetases. EMBO J 14:3461-71