New publication of the MITO-team in NAR molecular Medicine
Mitochondrial CRISPR system : new paper in NAR Mol Med by the MITO-team
New publication of the MITO team about endonuclease G
The MITO team participated in an international collaborative study with the National Heart, Lung and Blood Institute (NIH, Bethesda, MD, USA), now published in Proceedings of National Academy of Sciences of USA.
New publication from the Becker & Tarassov-Smirnov teams: AARS Online: A collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases
AARS Online is an interactive Wikipedia-like tool curated by an international consortium of aminoacyl-tRNA synthetase (aaRS) experts. Accessible at www.aars.online, it is a free resource to delve into the world of aaRSs, key players of the mRNA translation process. AARS Online systematizes existing knowledge about aaRSs by showcasing a…
New publication in Nature Cell Biology by the MITO team in collaboration with the University of Liège
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to cancer development through regulation of codon-specific messenger RNA translation. Specific aminoacyl-tRNA synthetases can either promote or suppress tumourigenesis. Here we show that valine…
GTPase Era at the heart of ribosome assembly
Our comprehensive review on the fascinating ribosome assembly GTPase Era/ERAL1 is out!
Our detailed CoLoC-seq protocol is published in Bio-protocol
Anyone who wants to have a clear & reliable idea about RNA localisation inside/outside membrane-bounded organelles, extracellular vesicles, or viral particles can now use this detailed protocol. It includes all reagents & equipment necessary to perform CoLoC-seq experiments, a step-by-step protocol, and useful tips for data analysis &…
Actualités
New publication of the MITO-team in NAR molecular Medicine
Mitochondrial CRISPR system : new paper in NAR Mol Med by the MITO-team
Chaires juniors dans le domaine de recherches sur les mitochondries
Le Laboratoire d'excellence (LabEx) MitoCross annonce l'appel aux candidatures de deux chaires juniors dans le domaine de recherches sur les…
We welcome XuChu Duan, a visiting researcher from the Nantong University!
XuChu, who is a specialist in zebrafish and developmental biology, is doing his sabbatical in our team. He will work on the mechanistic roles of YBEY…
USIAS 2020 award for Alexandre Smirnov
The Institute for Advanced Studies at the University of Strasbourg (USIAS) is committed to supporting an original type of research and potentially…
The MITO team welcomes a new PhD student, Théo Markezic
Théo Markezic, funded by IMCBio, starts his PhD studies in the "RNA-binding hubs" group.
The MITO team welcomes a new member, Dr Marie SISSLER (CNRS)
Dr Sissler works on diverse aspects of mitochondrial RNA biology. She is particularly interested in mitochondrial aminoacyl-tRNA synthetases in as…
Anne-Marie Heckel à la rencontre des Lycéens
Anne-Marie Heckel, ingénieure de l'équipe MITO, avait présenté nos thématiques de recherche aux lycéens. La rencontre a été mise en lumière par deux…
Le projet d’École Universitaire de recherche en biologie moléculaire et cellulaire intégrative incluant le LabEx MitoCross - lauréat du Programme d’investissements d’avenir.
Basé sur un regroupement stratégique des forces strasbourgeoises en biologie moléculaire et cellulaire des trois Laboratoire d'excellence (LabEx) INRT…
Inauguration du LabEx MitoCross
Le lancement officiel du laboratoire d'excellence MitoCross, qui implique deux équipes de l'unité (N. Entelis & I. Tarassov et H. Becker), a été…
Le consortium MitoCross se dote d'un site web !
L'objectif global du consortium MitoCross est d'approfondir les connaissances et mécanismes moléculaires fins gouvernant la biogenèse des…
LabEx : La Mitochondrie Strasbourgeoise à l'Honneur
2 équipes de l'unité ont été labélisées MitoCross Le projet Laboratoires d’Excellence (LabEx) Investissement d’Avenir vise à soutenir des projets…
Focus
Quand l’évolution s’invite au labo
Alexandre Smirnov a parlé de l’évolution expérimentale dans le cadre des "Rencontres" du « Jardin des Sciences de l’Université de Strasbourg » (Palais…
Focus
Bacteria, mitochondria, ribosomes & evolution at the Fête de la Science 2023
Friday, October 13, 2023 was the school day in the Village des Sciences, at the Palais Universitaire. The MITO team was there to familiarise the…
Publications
New publication of the MITO team about endonuclease G
The MITO team participated in an international collaborative study with the National Heart, Lung and Blood Institute (NIH, Bethesda, MD, USA), now…
New publication from the Becker & Tarassov-Smirnov teams: AARS Online: A collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases
AARS Online is an interactive Wikipedia-like tool curated by an international consortium of aminoacyl-tRNA synthetase (aaRS) experts. Accessible at…
New publication in Nature Cell Biology by the MITO team in collaboration with the University of Liège
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to…
GTPase Era at the heart of ribosome assembly
Our comprehensive review on the fascinating ribosome assembly GTPase Era/ERAL1 is out!
Our detailed CoLoC-seq protocol is published in Bio-protocol
Anyone who wants to have a clear & reliable idea about RNA localisation inside/outside membrane-bounded organelles, extracellular vesicles, or viral…
New publication by MITO-team
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
Review on the evolutionary aspects of the FinO/ProQ family proteins
Our review paper on the evolutionary significance of RNA-binding proteins of the FinO/ProQ family has been published in Bioscience Reports.
Editorial for the Special issue "Research progress in RNA-binding proteins" - International Journal of Molecular Sciences
We are proud to present a great collection of papers published in the Special issue "Research progress in RNA-binding proteins" of International…
The MITO team created an innovative subcellular transcriptomics approach, CoLoC-seq - Nucleic Acids Research
A new genome-wide method that marries classical enzymatic kinetics, deep sequencing, and mathematical modelling - CoLoC-seq - has been created in the…
MITO team : editorial in Frontiers Physiology
Editorial for a special issue of Frontiers Physiology
New publication of the MITO team in Computational and Structural Biotechnology Journal
Theoretical and mathematical biology paper about hub-centred RNA-protein networks
New publication of the MITO team in Nucleic Acids Research
Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24. pii: gkab1227. doi:…
Our paper in collaboration with the Alya Venyaminova's team has been published in Molecules
Meschaninova MI, Entelis NS, Chernolovskaya EL, Venyaminova AG (2021) A versatile solid-phase approach to the synthesis of oligonucleotide conjugates…
Congratulations on a fantastic 2021 series of review & protocol papers from the MITO team!
Our big review on stable RNPs and the complexomic approaches to profile them , including Grad-seq, co-authored with the Jörg Vogel's lab, is availbale…
A FASEB J. paper by the MITO team
The FASEB Journal Early View RESEARCH ARTICLE Open Access Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis…
New publication by MITO team in Neurology: Genetics
Karine Auré, Guillemette Fayet, Ivan Chicherin, Benoit Rucheton, Sandrine Filaut, Anne-Marie Heckel, Julie Eichler, Florence Caillon, Yann Péréon,…